Last Updated on November 4, 2021 by BVN

S. E. Williams |

As Inland Empire residents line-up to receive vaccine boosters, parents are preparing to vaccinate their young children between the ages of 5 and 11 years based on the Centers for Disease Control and Prevention’s (CDC) approval Tuesday of the FDA recommendation made a few days ago. 

In the meantime, healthcare professionals, community leaders, and others continue working to persuade the unvaccinated to take the COVID-19 vaccine to keep the virus contained and minimize the spread. 

At the same time, the CDC is  also softening the ground for immunocompromised individuals as a way to  prepare them for the very real possibility of a fourth COVID-19 shot in 2022.

Last week the Centers for Disease Control and Prevention (CDC) updated its COVID-19 Vaccine guidelines detailing new information for some adults with weakened immune systems.

Although the agency had initially stressed that for public health purposes, immunocompromised people who had completed a primary vaccine series of Pfizer or Moderna or taken a single dose of Johnson and Johnson were considered fully vaccinated after two weeks, in August, the agency reconsidered and recommended a third dose of COVID-19 vaccine for some immunocompromised individuals before ultimately recommending a third shot for all Americans.

A 4th dose of COVID-19 vaccine may be recommended for some  immunocompromised individuals in 2022. (source:

The CDC now reports a fourth dose is likely. “[R]educed vaccine effectiveness has been observed in immunocompromised participants compared to participants who are not immunocompromised in a limited number of studies.”

The agency points to several small studies that show an additional mRNA (Pfizer or Moderna) COVID-19 vaccine dose in some immunocompromised people who received a Pfizer or Moderna primary vaccine series may enhance antibody response.

Immunocompromised individuals who may be considered for an additional shot are those whose conditions and treatments include but are not limited to:

  • Active treatment for solid tumor and hematologic malignancies
  • Receipt of solid-organ transplant and taking immunosuppressive therapy
  • Receipt of CAR-T-cell therapy or HCT (within 2 years of transplantation or taking immunosuppression therapy)
  • Moderate or severe primary immunodeficiency
  • Advanced or untreated HIV infection
  • Active treatment with high-dose corticosteroids, etc.

In all instances immunocompromised individuals  are encouraged to  consult their physician for guidance. 

The CDC also notes the importance of encouraging everyone around these immunocompromised individuals to be vaccinated. Data shows vaccines are proven to be 90% effective against hospitalizations for COVID in the U.S.

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S.E. Williams

Stephanie Williams is executive editor of the IE Voice and Black Voice News. A longtime champion for civil rights and justice in all its forms, she is also an advocate for government transparency and committed to ferreting out and exposing government corruption. Stephanie has received awards for her investigative reporting and for her weekly column, Keeping it Real. Contact Stephanie with tips, comments. or concerns at